Treatment of wounds using ocean ingredients

In this new publication by Stenlund and colleagues, a novel wound dressing using TUNICELL was described and tested for bioactivity and safety ( 

Developing new and effective wound dressings is important since many patients suffer from chronic wounds that are difficult to heal. Treatments of wounds is an increasing burden on our healthcare system due to an aging population and prevalence of lifestyle related diseases such as diabetes. 

Stenlund et al. (2023)
The patches (a) were incubated at 37 °C, 5% CO2, in a humidified atmosphere during the analysis. The absorbance of DMEM + FBS blank was subtracted from each measurement. Protein release of Collex in 1 mL DMEM supplemented with 10% FBS and 1% Pen/Strep determined by absorbance at 280 nm (b), n = 5 presented as a mean ± SD.

Wounds that are hard to heal may cause both physical and psychological distress for patients, as well as leading to prolonged and repeated hospital stays. New and innovative wound dressings are therefore important for both patients and society. 

The novel wound dressing created by Regenics using marine ingredients, including TUNICELL, was found to be safe, non-toxic and non-irritant. Indeed, a previous study by Apelgren et al. 2022 (, also demonstrated that TUNCELL is biocompatible according to ISO10993-6. Gilljam et al. 2023 ( showed that TUNICELL based wound dressings improved healing in burn wounds compared to an existing alternative on the market. These studies provide proof of concept for the use of TUNICELL in wound dressing applications. At Ocean TuniCell we are proud to contribute to this important field. 

Dr. Hoareau, researcher at Ocean TuniCell, points that this study is one more evidence on the benefit of using TUNICELL for wound healing applications, as our hydrogel has strong hydration ability.

Stenlund P, Enstedt L, Gilljam KM, Standoft S, Ahlinder A, Lundin Johnson M, Lund H, Millqvist Fureby A, Berglin M (2023) Development of an All-Marine 3D Printed Bioactive Hydrogel Dressing for Treatment of Hard-to-Heal Wounds. Polymers. 15(12):2627,